Targeted biopsy processes alone are not good enough for accurate diagnosis

A significant number of patients have wanted to believe that, with the coming of targeted biopsies based on multiparametric MRI imaging, the need for “random” systematic biopsies (e.g., standard 10- or 12-core biopsies) would go away. … READ MORE …

“Basket” studies — another new class of clinical trial

Although it has no immediate relevance to the treatment of prostate cancer, it is worth noting that the results of the very first, completed and published “basket” type of clinical trial appear in this week’s issue of the New England Journal of Medicine (NEJM). … READ MORE …

mpMRIs, targeted biopsies, and the accuracy of Gleason grading

A new study that is in press on line in the Journal of Urology addresses, very reasonably, the question of whether using targeted biopsy methods based on multiparametric MRI (mpMRI) data is improving our ability to accurately assess patient’s Gleason grades and scores prior to decisions about treatment. … READ MORE …

A new “gold standard” for detection of prostate cancer?

An article just published in the Journal of Urology argues that, ” The gold standard for cancer detection in primary biopsy is [now] a combination of systematic and targeted cores.” . READ MORE …

MRI/TRUS fusion biopsies in men with PSA values < 5.2 ng/ml

There is a distinctly “odd” paper in the December 2014 issue of the Journal of Urology on optimization of the use of MRI/TRUS fusion-guided biopsies in men suspected of having prostate cancer. … READ MORE …

Early data on targeted focal therapy in treatment of localized prostate cancer

The potential role of targeted focal therapy in the management of localized prostate cancer is yet to be well-defined, so a paper just published on line in the Journal of Urology is of value in helping us to set our expectations. … READ MORE …

The role of MRI scanning prior to prostate biopsies

A pair of articles currently scheduled for publication in the December issue of the Journal of Urology has just appeared on line under the title “MRI before prostate biopsy — yes or no?” Unfortunately for our readers, access to this pair of articles is limited to subscribers to the journal (unless you want to pay), and there is no abstract. So we will try to summarize the key points. … READ MORE …