Projecting risk for metastasis after radical prostatectomy

A new paper in Clinical Genitourinary Cancer has provided us with some more detailed information about risk for metastasis in men with recurrent prostate cancer after first-line surgery. … READ MORE …

How anxiety affects prostate cancer patients on active surveillance over time

“Anxiety” of different types is a problem associated with every diagnosis of prostate cancer. Such anxiety comes with particular implications for men implementing active surveillance as an initial management strategy after initial diagnosis with very low-, low-, or favorable intermediate-risk prostate cancer. … READ MORE …

Time to death among men with nmCRPC by NCCN risk group

One of the abstracts to be presented at ASCO this year gives us some insight into risk for and time to death among men with non-metastatic but castration-resistant prostate cancer (nmCRPC). … READ MORE …

Numbers progressing and time to progression on active surveillance

A new study just published in the World Journal of Urology has provided us with data from the Prostate Cancer Outcomes Registry — Victoria (in Australia) on the progression of men initially managed on active surveillance. … READ MORE …

Now here’s a REALLY unsurprising piece of news!

A new report in the journal JAMA Oncology is said to have detailed “the psychological damage” that a cancer diagnosis “often leaves in its wake for patients.” … READ MORE …

Long-term quality of life for men on active surveillance

According to a paper presented today at the annual meeting of the European Association of Urology (EAU) in Munich, Germany, men on a structured active surveillance (AS) protocol have a high, long-term quality of life on follow-up. … READ MORE …

How long is long enough? Length of follow-up on clinical trials for primary treatments

Many of us are faced with the difficulty of choosing a primary therapy based on data from clinical trials with follow-up shorter than our life expectancy. How can we know what to expect in 20 or 30 years? … READ MORE …

Trends in the management of localized prostate cancer: 2000 to 2010

The international trend back toward increased use of more conservative management techniques (e.g., active surveillance and watchful waiting) for men with low-risk disease is again indicated in data from the Anglian region of the National Health Service in the UK. … READ MORE …

Survival times among men with biochemically recurrent prostate cancer

It would hardly come as a shock to most experienced prostate cancer advocates and patients to learn that there is an association between survival time and the aggressiveness of a patient’s cancer at the time of diagnosis if that cancer progresses. … READ MORE …

How much time is there to make decisions about treatment for low-risk patients?

In recent years there has been a widely acknowledged, if unconfirmed, assumption that men initially diagnosed with low-risk prostate cancer (clinical stage T1-2a, PSA < 10 ng/ml; and Gleason 3 + 3 = 6 or lower) had plenty of time to come to a good decision about their management options, and did not need to rush such decisions. … READ MORE …

Measuring outcomes after treatment for men after active surveillance

A new paper just published in the Journal of Urology has again shown (in a relatively small group of men) that radical prostatectomy appears to be curative for men who have  treatment after an initial on active surveillance, and then some indication of increased risk, but … READ MORE …

Surprise … outcomes after radiation therapy have improved over the past 20 years!

OK … So this isn’t really a surprise at all. Data from the radiation oncology group at the M. D. Anderson Cancer Center in Houston have apparently shown that — at least at that one major comprehensive cancer cancer — outcomes after external beam radiation therapy for prostate cancer were significantly better by 2007 than they were in the late 1980s. … READ MORE …

Time-related loss of erectile function after low-dose-rate brachytherapy

It has long been understood that erectile function after first-line treatment for localized prostate cancer is affected by (a) erectile function before treatment and (b) elapsed time after treatment. However, the available data offering a careful analysis of the chronology of erectile function after first-line treatment of localized prostate cancer has been limited. … READ MORE …

Variation of PSA values over time in individual patients

One of the problems with the use of the PSA test as an indicator of risk for prostate cancer is that the PSA values of specific individuals can vary over time … whether cancer is present or not. … READ MORE …

Predicting time to recovery of continence after surgery

A group of German researchers has developed a method to predict the duration of urinary incontinence after radical prostatectomy based on potential risk factors. … READ MORE …