Posted on August 12, 2021 by Sitemaster
For many years your sitemaster has been advising patients that overly early use of androgen deprivation therapy (ADT) in many men with progressive prostate cancer is not necessarily the best decision (for a number of possible reasons). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: ADT, androgen, deprivation, initiation, metastasis., timing | 9 Comments »
Posted on April 21, 2020 by Sitemaster
TROG 01.03 RADAR, begun in 2003, was a (partly) randomized clinical trial to help optimize therapy of unfavorable-risk patients. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, brachy boost, dose, extent, external beam, radiation, therapy, timing | Leave a comment »
Posted on September 25, 2017 by Sitemaster
A new study in BJU International has shown the importance of waiting at least 3 weeks after initiation of androgen deprivation therapy (ADT) until initiation of docetaxel chemotherapy in the treatment of men with newly diagnosed, metastatic, hormone-sensitive prostate cancer (mHSPC). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, chemotherapy, deprivation, docetaxel, hormone-sensitive, metastatic, neutropenia, risk, timing | 2 Comments »
Posted on March 28, 2017 by Sitemaster
In spite of data suggesting that brachy boost has better outcomes for high-risk patients, it is being utilized less often and surgery is being utilized more often. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: "high risk", adjuvant, post-surgery, radiation, salvage, therapy, timing | 7 Comments »
Posted on September 21, 2016 by Sitemaster
Another subject that has come up a lot recently is when to have salvage radiation. It is always a pressing decision for those 30 percent of prostatectomy patients who have detectable PSA after prostatectomy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, outcome, radiation, salvage, timing | 12 Comments »
Posted on August 9, 2016 by Sitemaster
Several clinical trials have established that adjuvant radiation reduces the risk of biochemical recurrence, but only one trial looked at and demonstrated an improvement in metastasis-free survival and prostate cancer-specific survival. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, radiation, salvage, therapy, timing | 7 Comments »
Posted on April 8, 2016 by Sitemaster
A newly published article in the journal Science Translational Medicine has questioned the merits of treating prostate cancer patients with immunotherapies while they are simultaneously being treated with medical forms of castration (androgen deprivation therapy or ADT), chemotherapy, and/or radiation therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, benefit, chenotherapy, combination, immunotherapy, radiation, risk, timing | 6 Comments »
Posted on February 27, 2016 by Sitemaster
For many years now, The “New” Prostate Cancer InfoLink has argued (on the basis of no good data at all) that starting to do Kegel exercises prior to having surgery for prostate cancer was likely to be able to accelerate recovery of good continence after one’s surgery. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: exercise, floor, Kegel, muscle, pelvic, surgery, timing | 1 Comment »
Posted on May 21, 2015 by Sitemaster
A combination of travel and other commitments made it difficult for your sitemaster to complete his summaries of significant information presented at this year’s annual meeting of the American Urological Association (AUA), so here’s the final wrap-up. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: active, ADT, androgen, deprivation, supplement, surveillance, testosterone, timing | 5 Comments »
Posted on April 15, 2015 by Sitemaster
The heading above is the title of a Reuters-generated article on the Medcape Oncology web site. The article is based on a new review article just published in BJU International. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: benefit, intervention, post-treatment, psychosocial, quality of life, timing, value | 4 Comments »
Posted on April 7, 2015 by Sitemaster
Two analyses of Italian and US databases have investigated whether delaying initiation of radiation therapy could diminish the side effects of radiation after prostatectomy. The conventional wisdom is that waiting longer allows the newly cut tissues more time to heal completely before the onslaught of radiation. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, complications, post-surgery, radiation, salvage, side effects, timing | Leave a comment »
Posted on January 14, 2015 by Sitemaster
In a previous article, we looked at evidence that a low detectable level of PSA predicts eventual biochemical recurrence (a confirmed PSA greater than 0.2 ng/ml) when there is aggressive pathology. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, recurrence, risk, salvage, timing | 44 Comments »
Posted on January 4, 2015 by Sitemaster
Patients and their doctors often have to make a critical decision soon after surgery – at what point after surgery, if at all, should salvage radiation therapy be started? … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, radiation, salvage, timing | 11 Comments »
Posted on January 20, 2011 by Sitemaster
There has long been discussion about the appropriate and inappropriate uses of androgen deprivation therapy (ADT) in the management of progressive prostate cancer. The “New” Prostate Cancer InfoLink has regularly commented on the inherent dangers of using ADT to “manage PSA levels” as opposed to managing a patient’s actual clinical condition. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation, hormone, therapy, timing | 9 Comments »
Posted on April 15, 2010 by Sitemaster
The question of when one should initiate hormone therapy in a man who has a rising PSA after radiation therapy has long been a topic of controversy. And a reanalysis of data from RTOG 85-31 has not helped to give us a definitive answer. … READ MORE …
Filed under: Management, Treatment, Uncategorized | Tagged: ADT, androgen deprivation therapy, outcome, radiotherapy, timing | Leave a comment »