SBRT has equivalent toxicity with 5 treatments and 12 treatments: an update

We first reported data from the results of the RTOG 0938 trial in January 2016 when they were presented at the Genitourinary Cancers Symposium in that year. These results have now been formally published, and there are some changes to the data on publication, so Allen Edel has provided an update. … READ MORE …

Safety limits of SBRT dose escalation

In a recent commentary, we saw that the lack of a standard of care for stereotactic body radiation therapy (SBRT) dose escalation may put patients at risk when dose limits are pushed beyond what is customarily considered effective and safe. … READ MORE …

SBRT has equivalent toxicity when given with 5 and 12 treatments

Data reported at the recent Genitourinary Cancers Symposium have shown that the toxicities associated with stereotactic body radiation therapy (SBRT) are acceptable and similar whether the radiation is give as 5 or 12 doses. … READ MORE …

Something you can do NOW about the cost of care and “financial toxicities”

In an article in the October 25 issue of The ASCO Post, Dr. Jonas de Souza of the University of Chicago has introduced a new initiative to help all cancer patients and their doctors address the increasing problems associated with the costs of cancer care. … READ MORE …

The direct “financial toxicity” of cancer diagnosis and treatment

An interesting new paper in Cancer has offered us a sophisticated assessment of the effects of a diagnosis of and treatment for cancer on employment and income of all adults (aged 18 and older) and of adults in their  prime working years (aged from 25 and 64). … READ MORE …

Longer time between treatments reduces SBRT rectal toxicity

There are many details of stereotactic body radiation therapy (SBRT) that may be optimized over the coming years. Among them is the optimum treatment schedule — i.e., how far apart should the treatments be spaced? … READ MORE …

Is SBRT more toxic than IMRT in treatment of localized prostate cancer?

A new paper, published online today in the Journal of Clinical Oncology, suggests that stereotactic body radiation therapy (SBRT, commonly delivered using the CyberKnife system) has a higher risk for genitourinary (GU) toxicity than intensity-modulated radiation therapy (IMRT). … READ MORE …

Acute and mid-term side effects of high-dose, image-guided IMRT in first-line treatment of localized prostate cancer

Two recent papers have reported data relevant to the application of high-dose, image-guided, intensity-modulated forms of radiation therapy (IGRT/IMRT) in the first-line treatment of men with localized prostate cancer. … READ MORE …

Toxic side effects of adjuvant, salvage IMRT post-surgery

Prostate cancer patients are commonly concerned about the potential risks for side effects associated with adjuvant and salvage radiation therapy after a preceding, first-line, radical prostatectomy. … READ MORE …

GI toxicity, radiation therapy, and androgen deprivation

For men undergoing the combination of external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT), for treatment of prostate cancer there is a significant risk for gastrointestinal (GI) toxicity over time. … READ MORE …

Adverse toxicities of high-dose PBRT: a Phase II clinical trial

ACR 03-12 is a Phase II clinical trial designed by the American College of Radiology to test the safety and efficacy of 82 GyE (Gray equivalent) delivered using conformal proton beam radiation therapy (PBRT) for the treatment of localized prostate cancer. … READ MORE …

Acute and late radiation toxicities of proton beam radiation therapy

Over the years there have been almost no publications addressing the complications of proton beam radiation therapy (PBRT) among well-defined series of prostate cancer patients. With the number of PBRT centers now growing fast, good data on the side effects of PBRT are an urgent priority. … READ MORE …

Prostate cancer news reports: Friday, May 22, 2009

Today’s news reports cover items on:

  • Gene expression and prostate cancer progression
  • Risk of complications from in-office prostate biopsy
  • Post-RALP voiding function
  • Urinary toxicities after IMRT-SIB
  • Drugs in development for CRPC … READ MORE …

Thursday’s news reports: February 19, 2009

Today’s important news reports address:

  • 5- and 7-year survival data following iodine-125 permanent implant brachytherapy
  • Risks associated with low levels of lymphocyte apoptosis in patients receiving radiation therapy
  • Stiffening of the large arteries in men receiving antiandrogen therapy
  • The status of the toremifene and denosumab applications for approval for marketing in the USA … READ MORE …