The androgen-sensitive to androgen-resistant transition: an hypothesis

A media release issued on Tuesday this week by a usually highly respected medical center in the Los Angeles area is misleadingly entitled, “Hormone therapy can make prostate cancer worse, study finds”. … READ MORE …

Just how important is this scientific paper?

The most frequent alteration in the prostate oncogenome is loss of chromosome (chr) 8p21 that has been associated with loss of NKX3.1 homeobox gene.
… READ MORE …

Is Twist1 a key to cancer metastasis?

The other day we reported on a study by Bensawy et al. supporting the idea that epithlial-to-mesenchymal transition or EMT might be an underlying mechanism driving prostate cancer metastasis. … READ MORE …

Predicting metastatic progression of prostate cancer after first-line therapy

The spreading of prostate cancer cells from the prostate to distant sites in the body (“metastasis”) is a critical factor in why prostate cancers lead to patients’ deaths, … but we still don’t really know what triggers prostate cancer cells (or any other cancer cells for that matter) to metastasize. … READ MORE …