Prostate cancer news update: Tuesday, August 26

There are several interesting news items today, as follows:

  • Ethnic variation in the performance of PSA and PSA density as markers for risk of prostate cancer
  • Potential underuse of active surveillance in eligible patients
  • Application of active surveillance in a 40-patient case series
  • The potential to eliminate the need for a urethral (Foley) catheter post-surgery
  • Circulating tumor cell levels as a predictor for response to androgen deprivation therapy … READ MORE …

Obesity, statins, and risk for prostate cancer

A recent epidemiologic study in King County, Washington, has found an increased risk for prostate cancer associated with statin use among obese men. … READ MORE …

Prostate cancer news update: Monday, August 25

Two reports just published would appear to confirm individual patient experiences in the treatment of advanced disease:

  • The impact of ADT on body composition
  • The effects of docetaxel chemotherapy in men aged ≥ 75 years … READ MORE …

Prostate cancer news update: Saturday, August 23

Todays’ reports contain some interesting data, although it is not entirely clear how they should best be applied in the diagnosis and potential management of patients at risk:

  • A study of patient preferences and decision making about how to be treated
  • Why some Brazilian men reject digital rectal examination (fewer that you might expect)
  • The natural history of high-grade prostatic intraepithelial neoplasia (HGPIN)
  • The potential of ferumoxtran-10 (Combidex) in diagnosis of lymph node metastases … READ MORE …

Prostate cancer news update: Tuesday, August 19

Recent publications reported on today include:

  • Demonstration of the validity of the Epstein criteria in defining pathologically insignificant prostate cancer
  • A review of the value of sildenafil (Viagra) and similar products in treatment of erectile dysfunction among prostate cancer patients
  • A review of the significance of “gene fusion” and its relevance in prostate cancer … READ MORE …

Your prostate cancer news update: Saturday, August 16

There is in fact a good deal of news this weekend. Information about four items are provided below and we will discuss additional news items tomorrow. Items in this article include:

  • The relative views of Canadian urologists and radiation oncologists toward PSA screening and treatments for localized disease
  • A complex form of investigational immunotherapy for localized prostate cancer
  • Data suggesting the possibility of a survival benefit resulting from treatment of  hormone refractory prostate cancer patients with docetaxel (Taxotere) + ASA404 (an investigational drug)
  • A new review of psychosocial issues and their impact on management of prostate cancer … READ MORE …

What’s in the prostate cancer news: Friday, August 15

In today’s prostate cancer news update we report on:

  • Awareness of the PSA test in men with other recognized health risks
  • A new urine test that may differentiate between prostate cancer and BPH
  • Markers for the likelihood of effectiveness of androgen deprivation from an ongoing Finnish multicenter trial … READ MORE …

The day’s news update: Thursday, August 14

Today’s prostate cancer news update includes information related to the following areas:

  • Long-term survival of patients with PSA levels ≥ 50 ng/mL who have been treated with radical prostatectomy
  • The current role of bone imaging in the managment of prostate cancer
  • The potential of targeted therapy for androgen-independent prostate cancer, based on expression of specific molecular markers … READ MORE …

More prostate cancer news: Tuesday, August 12

There are several interesting new papers reported today, and two very important ones (which have been addressed in separate posts). This post addresses:

  • A retrospective analysis of the relative predictive value of positive surgical margins following radical prostatectomy in the pre- and post-PSA eras
  • A new nursing model for management of urinary incontinence post-prostatectomy
  • The importance of assessing risk for transitional zone prostate cancer in patients already diagnosed with bladder cancer, and
  • A review of developing strategies for the treatment of late-stage prostate cancer
  • Other reports today address adjuvant vs. salvage radiation therapy and quality of care in management of early stage prostate cancer. … READ MORE …

The Darwinian evolution of cancers

In a fascinating study by scientists from The Institute of Advanced Studies at Princeton and the University of California, Yeang et al.  are reporting that a molecular, Darwinian, “survival of the fittest” scenario appears to play out as gene mutations seek to survive through cancerous tumors. … READ MORE …

The weekend prostate cancer news update: Saturday, August 9

Today’s prostate cancer news contains important information for Vietnam veterans from a study carried out on the incidence of prostate cancer among veterans cared for through the Northern California VA Health System. It is also of considerable significance regarding prostate cancer risk among the Vietnamese people. … READ MORE …

All the prostate cancer news for Friday, August 8

Today’s news items all focus on issues that are closely connected to the recent and controversial  guidelines issued by the US Preventive Services Task Force:

  • The accuracy of current methods for predicting the likelihood of clinically insignificant (indolent) prostate cancer
  • The management of patients found to have incidental prostate cancer on treatment for benign prostatic hyperplasia (BPH), and
  • The risks of overtreatment of men in their 70s and 80s after a diagnosis of prostate cancer … READ MORE …

New gene-based diagnostic test for prostate cancer

Health Discovery Corporation (HDC)  has announced the successful completion of a double-blind, Phase III trial of its new gene-based molecular diagnostic test for prostate cancer. … READ MORE …

The prostate cancer news de jour: Thursday, August 7

There is an interesting report in Urology on the relationship between indicators of sexual and somatic development and risk for prostate cancer. We would observe, however, that this is a relatively small, retrospective study and is highly dependent on self-reported patient data. … READ MORE …

The prostate cancer news update: Tuesday, August 5

So after a few days becalmed in a world of minimal prostate cancer news … we have a fine controversy to revisit and some other interesting titbits to gnaw on … … READ MORE …