Modern 5-year outcome data after radiotherapy for very high-risk patients

A newly published paper reports 5-year outcome data from a series of men initially diagnosed with very high-risk, but localized prostate cancer — all of whom were treated with either dose-escalated external beam radiation therapy (EBRT) or pelvic radiation + permanent interstitial seed implantation (combined modality radiotherapy or CMRT). … READ MORE …

Does a PSA level > 20 ng/ml preclude radical prostatectomy?

There is an interesting report today from an Italian clinical research team on the outcomes of radical prostatectomy in men with higher than normal PSA levels (i.e., 20 ng/ml and higher) at time of diagnosis. We know that all prostate cancer patients with PSA levels > 20 ng/ml are now customarily classified as having high-risk disease. … READ MORE …