Results of the RADAR trial at 7.4 years of follow-up

The RADAR trial (also known as TROG 03.04) was a randomized trial of 6 months of androgen deprivation therapy (ADT) + radiation therapy versus 18 months of ADT + radiotherapy, with or without additional zoledronic acid therapy, in men with intermediate- and high-risk, locally advanced prostate cancer. … READ MORE …

Ibandronate for relief of pain in men with metastatic prostate cancer

According to another study presented at the European Multidisciplinary Cancer Congress (EMCC) in Stockholm this weekend, the bone-strengthening bisphosphonate ibandronate (Boniva®) seems to work just as well as radiotherapy for the management of pain associated with prostate cancer that has metastasized to the bones. … READ MORE …

Featured in “day 1” at the ASCO annual meeting

Saturday was never going to be a major day for prostate cancer at the annual meeting of the American Society for Clinical Oncology (ASCO) here in Chicago. … READ MORE …

Prostate cancer news reports: Tuesday, April 20, 2010

In today’s news reports we note new articles dealing with:

  • Biopsy protocols, patient selection, and focal therapy
  • Tertiary Gleason pattern 4/5 and risk for progression post-RP
  • Evolving data on the uses of bisphosphonates and denosumab
  • SKIs in treatment of advanced forms of prostate cancer … READ MORE …

Denosumab: “better” than zoledronate?

A media release issued yesterday by Amgen claims that denosumab “demonstrated superiority” over zoledronate (Zometa) in a randomized, multi-center, Phase III clinical trial in prostate cancer patients with bone metastases. … READ MORE …

Is denosumab “better” than Zometa at preventing skeletal events?

Amgen, the developer of denosumab (also known as RANK-L) has released data today from a head-to-head trial of their drug vs. zoledronate (Zometa) in the management of patients with advanced breast cancer and bone metastases. … READ MORE …