Tokai stops Phase III trial of galeterone

Alas, Tokai Pharmaceuticals has announced this morning that it has been forced to discontinue the ARMOR3-SV trial of its investigational drug galeterone in the treatment of patients with castration-resistant prostate cancer (CRPC) who are expressing the AR-V7 mutation. … READ MORE …

The politics of PSA testing

We continue to see a steady stream of articles in the cancer literature that appears to be designed to influence the thinking of the U.S. Preventive Services Task Force (USPSTF) as they reconsider the value of PSA testing in assessment of risk for prostate cancer. … READ MORE …

That “rise” in the incidence of metastatic prostate cancer

Well … Don’t say we didn’t warn you. The American Cancer Society (ACS) and others are now saying that the study suggesting a rise in the incidence of metastatic prostate cancer from 2004 to 2013 has serious flaws. … READ MORE …

A rise in the incidence of metastatic prostate cancer from 2004 to 2013

A newly published article in the journal Prostate Cancer and Prostatic Diseases suggests that there has been a relative 72 percent rise in the incidence of metastatic prostate cancer from 2004 to 2013 — mostly among men of 55 to 69 years of age. … READ MORE …

Defining value in the management of prostate cancer

Many years ago, among his other famous quotations on the subject of prostate cancer, Willet Whitmore, considered by many to be the “father” of urologic oncology, stated the following: … READ MORE …

Change at the American Cancer Society?

After just over a year on the job, the American Cancer Society’s new president has started to talk publicly about ongoing transformation at the ACS. … READ MORE …

A first-in-human trial of actinium-225-PSMA-617

Among the more interesting developments in radiation oncology/nuclear medicine in recent years are novel therapies created by attaching radioactive isotopes to molecules (called ligands) that attach to the prostate-specific membrane antigen (PSMA). … READ MORE …

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