Posted on October 20, 2021 by Sitemaster
As many readers will already be aware, the National Comprehensive Cancer Network (NCCN) has recently removed the word “preferred” from its statement regarding the use of active surveillance (AS) as an appropriate form of management of men with low-risk forms of localized prostate cancer. A broad swath of specialists in the initial management of low-rise disease, as well as many in the patient advocacy community, have been highly critical of this change to the NCCN guidelines. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment, Uncategorized | Tagged: active, guidelines, low-risk, NCCN, surveillance | 7 Comments »
Posted on October 19, 2021 by Sitemaster
Three major randomized clinical trials and a meta-analysis have proved that for most men waiting for early signs of recurrence after prostatectomy (e.g., three consecutive PSA rises or a PSA of 0.1 ng/ml) to give radiation gave the same outcome as immediate (“adjuvant”) radiation (see this link). But there are exceptions. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvaant, earky, mortality, outcome, post-prostatectomy, risk, salvage | Leave a comment »
Posted on October 17, 2021 by Sitemaster
At the end of September, the Prostate Cancer Foundation appointed Charles {“Chuck”) Ryan, MD — formerly of the University of California, San Francisco, and the University of Minnesota — as the new President and CEO of the Foundation. And there will be two opportunities for patients to hear directly from Dr. Ryan in the near future. … READ MORE …
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Posted on September 22, 2021 by Sitemaster
Prostate Cancer International (PCaI) is proud to be an inaugural member of the new Prostate Cancer Impact Alliance (PCIA). PCIA’s shared vision is to advance education, research and equitable access to high quality care to better patient outcomes for men with prostate cancer. … READ MORE …
Filed under: Uncategorized | Tagged: advocacy, alliance, outcome, PCIA | 5 Comments »
Posted on September 21, 2021 by Sitemaster
Two educational programs are scheduled on Wednesday, September 29. The two programs will be be very different: one for very early stage patients; the other for patients with progressive prostate cancer at risk for (or already diagnosed with) de novo metastatic, hormone-sensitive prostate cancer (mHSPC) … READ MORE …
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Posted on August 19, 2021 by Sitemaster
The decision about whether or not to treat the entire pelvic lymph node area along with the prostate (called whole pelvic radiation therapy or WPRT) or to treat just the prostate with a margin around it (called prostate-only radiation therapy or PORT) has long been a matter of judgment. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: outcome, pelvic, prostate-only, radiation, risk | 9 Comments »
Posted on August 19, 2021 by Sitemaster
A new paper by Meissner et al. has reported important, long-term data on fear of recurrence and biochemical progression of prostate cancer among a large cohort of German patients undergoing radical prostatectomy. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: fear, outcome, recurrence, surgery, survey | 3 Comments »
Posted on August 12, 2021 by Sitemaster
For many years your sitemaster has been advising patients that overly early use of androgen deprivation therapy (ADT) in many men with progressive prostate cancer is not necessarily the best decision (for a number of possible reasons). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: ADT, androgen, deprivation, initiation, metastasis., timing | 5 Comments »
Posted on August 11, 2021 by Sitemaster
In 2016, we looked at the Candiolo risk stratification system for radiation therapy. To our knowledge, it has not been prospectively validated or widely adopted. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: nomogram. radiation, predictive, prognosis, risk, stratification, therapy | 4 Comments »
Posted on July 26, 2021 by Sitemaster
As of Friday (July 22), we had received more than 250 responses to our brief survey on research into active surveillance. Most of these are from patients and some from their familial supporters (spouses, partners, etc.). However,we are still interested in getting more input — especially from clinicians, including specialists, generalists, and allied health personnel like urology nurses! … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: active surveillance, AS, research | 2 Comments »
Posted on July 26, 2021 by Sitemaster
Three more upcoming webinars this week will deal with (a) the work-up of men with prostate cancer prostate cancer who progress after first-line therapy (such as surgery, radiation, etc.); (b) whether Gleason 6 disease should really be defined as “prostate cancer”; and (c) an update on the most current information related to the evaluation and management of men with prostate cancer appropriate for active surveillance. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: progression. active, surveillance, webinar | Leave a comment »
Posted on June 23, 2021 by Sitemaster
Three upcoming webinars deal with (a) the diagnosis and work-up of clinically significant forms of localized prostate cancer; (b) handling anxiety and related issues for men on active surveillance (AS); and (c) whether AS is appropriate for African Americans and others of African ethnicity. See below for details. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: education, patient, webinar | 1 Comment »
Posted on June 22, 2021 by Sitemaster
A diverse group of patients, patient advocates, patient spouses/supporters, physicians, and other researchers has come together, with funding support from the Patient Centered Outcomes Research Institute (PCORI), to plan a virtual conference for the fall of 2021. At that conference, we intend to discuss and identify new and evolving opportunities for research into the most appropriate, high-need, high-impact topics affecting the use of active surveillance (AS) for the management of favorable-risk forms of prostate cancer (i.e., low-risk and “favorable” intermediate-risk disease). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: active, research, surveillance | 5 Comments »
Posted on June 20, 2021 by Sitemaster
Back in 1989, the SWOG 8494 trial first showed that adding an antiandrogen (flutamide) to bilateral medical orchiectomy with an LHRH agonist (leuprolide acetate) extended median overall survival (OS) by 7 months in newly diagnosed men with metastatic, hormone-sensitive prostate cancer (mHSPC). … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation, hormone-sensitive, metastatic, mHSPC, overall, survival, SWOG 1216 | 1 Comment »
Posted on June 20, 2021 by Sitemaster
A large randomized clinical trial, SAKK 09/10, found that a salvage radiation dose of 64 Gy over 32 treatments had equivalent biochemical outcomes compared to 70 Gy over 35 treatments. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: radiation, SAKK 09/10, salvage | Leave a comment »
