New data on the genetics of aggressive prostate cancer, but …

A new paper in the Proceedings of the National Academy of Sciences suggests the existence of a subset of “hypermutated” cell lines in some forms of aggressive prostate cancer. … READ MORE …

Wednesday’s news reports: February 25, 2009 — Part 1

There has been a positive plethora of news reports over the past 24 hours, starting with the very important issuance of the AUA/ASCO guideline on the potential use of 5-ARIs for the prevention of prostate cancer. This will be just the first of at least three groups of news reports today! This report deals with:

  • A review of the role of IGF-I levels in development (and possible treatment) of prostate cancer
  • The lack of “race-specific” differences in PSA levels based on ancestry
  • An assessment of the feasibility of using genetic variants to test for prostate cancer risk
  • The availability of a research grade (not a clinical) test for sarcosine levels in tissues
  • Interim data on the investigational drug phenoxodiol … READ MORE …