The APCCC in Basel, Switzerland: Day 1

So in this series of reports on what happened at the 3rd Advanced Prostate Cancer Consensus Conference (APCCC) in Basel, Switzerland, we will not be trying to get into detail about exactly what data got presented each day. … READ MORE …

A national study of prostate cancer in African Americans

The National Cancer Institute has invested over $20 million in a new study that will attempt to enroll 10,000 African-American men who have been diagnosed with prostate cancer: the RESPOND study. … READ MORE …

The genetics of prostate cancer risk among African males

A newly published study from a group of researchers at the Garvan Institute in Scotland has again confirmed the apparent genetic risk for some forms of prostate cancer among men of African ethnic origin. … READ MORE …

Understanding the genetics of prostate cancer diagnosis and treatment

For those who are interested in this evolving topic, we recommend listening to Dr. Charles Ryan’s 16-minute-long discussion with Heather Cheng, MD, PhD, entitled “Genetic evaluation and counseling in prostate cancer treatment”. … READ MORE …

Another 63 genetic variants seem to affect risk for diagnosis with prostate cancer

Newly published research in Nature Genetics has reported the identification of yet another 63 new variants in the human genome that increase risk for a diagnosis of prostate cancer in males. This takes the total number of such variants identified to date to something approaching 175. … READ MORE …

Molecular biological reasons for switching to a healthier diet!

Two articles just published this week by a Boston-based research team have implicated Western high-fat diets in risk for metastasis of prostate cancer. … READ MORE …

FDA approves key genetic/genomic test for cancer mutations

According to reports from the Associated Press and others, some time late last Thursday the  US Food & Drug Administration (FDA) appears to have approved the use of the FoundationOne CDx genetic/genomic test for patients with “advanced or widely spread cancers.” A media release from Foundation Medicine is also available on line. … READ MORE …

Understanding genetics, genomics, and their utility in prostate cancer

Our friends at UroToday have just published a perfectly lovely lecture on this topic given by Prof. Lenny Gomella at the recent annual meeting of the Large Urology Group Practice Association (LUGPA). … READ MORE …

Predicting the future: what Genomic Health isn’t telling us (yet)

A media release issued  yesterday by Genomic Health, Inc., has suggested that the multi-gene Oncotype DX® Genomic Prostate Score™ is a strong predictor of risk for the development of metastasis and prostate cancer death in patients with early-stage prostate cancer. … READ MORE …

“Why gene tests for cancer don’t offer more answers”

An article with the above title appears to be scheduled for upcoming publication in Scientific American but is already available on line on the Scientific American web site. It may be of interest to a number of our readers. … READ MORE …

Personalized medicine is coming to life in management of advanced prostate cancer

A new study reported today in the New England Journal of Medicine is suggesting that every man with metastatic prostate cancer (regardless of his age or family history) should be tested for certain particular inherited mutations. … READ MORE …

Why inheriting a particular gene may be important for prostate cancer patients

An important poster that your sitemaster managed to “miss” at the recent ASCO meeting (because he was at another meeting while it was being presented) has just been discussed on the MedPage Today web site. … READ MORE …

What’s happening at the annual EAU meeting in Munich?

So our friends at UroToday have started providing reports on the key presentations that are being given at the annual meeting of the European Association of Urology, being held this year in Munich, Germany. Here are links to some interesting reports … READ MORE …

CureTalk program on imaging and genomics with Dr. David Lee

Yesterday evening we held a CureTalk program on the roles of new imaging and genomic/genetic tests in the diagnosis, work-up, and prognosis of prostate cancer with Dr. David Lee of the University of Pennsylvania. … READ MORE …

The biological evolution and metastasis of prostate cancer

A new research letter in the journal Nature has addressed issues related to the ways in which prostate cancer evolves over time from an initial, small, localized tumor to widespread, metastatic disease. … READ MORE …