How accurate is an initial, negative prostate biopsy at predicting risk for prostate cancer-specific mortality?

A new paper in this week’s issue of Lancet Oncology comes from analysis of data on the outcomes of > 60,000 men given a prostate biopsy for risk of prostate cancer in Denmark between 1995 and 2011 and followed for up to 20 years thereafter. … READ MORE ..

Letters to the Editor on interpretation of data from the ProtecT trial

In September last year, Hamdy et al. published the initial results of the ProtecT trial — a trial designed to compare overall outcomes at 10 years among > 1,600 men diagnosed with low- and intermediate-risk, localized prostate cancer and randomized to treatment by surgery, by external beam radiation therapy, or by active monitoring (a very basic form of active surveillance). … READ MORE …

Can phi density accurately predict risk for clinically significant prostate cancer?

A new article in BJU International has suggested the possibility that Prostate Health Index density (i.e., a patient’s phi score divided by his prostate volume) may be able to predict the probability of a finding of clinically significant prostate cancer on biopsy. … READ MORE …

Population-based rates of treatment for prostate cancer: 2007-2012

The population-based rate of Medicare patients getting treatment for prostate cancer dropped by 42 percent from 2007 to 2012 … but this drop did not occur in patients who had a high risk of dying from a cause other than prostate cancer within 10 years, who are arguably among those who least need immediate treatment for prostate cancer (and especially for low-risk forms of prostate cancer). … READ MORE …

Incidence, outcomes, ethnicity, and distant, de novo, metastatic prostate cancer

Diagnosis of men with distant, metastatic prostate cancer at first presentation (distant, “de novo”, metastatic prostate cancer) is a lot less common today than it was 30 or 40 years ago, but it does still happen on a regular basis. … READ MORE …

Prostate cancer in men with advanced bladder cancer

A new article in the journal Urologic Oncology has highlighted an association between the occurrence of advanced bladder cancer and the related finding of prostate cancer among such patients who have their prostate removed along with their bladder at the time of initial surgery  for the bladder cancer (i.e., a radical cystoprostatectomy). … READ MORE …

Prostate cancer statistics in America, 2017

As it does every year, the American Cancer Society (ACS) has just published it’s annual update cancer statistics update: Cancer Facts & Figures 2017. Those who are interested are of course welcome to peruse this detailed document for themselves. What follows is a quick summary of the prostate cancer-related data in the ACS update. … READ MORE …