Long-term use of 5-ARIs in low-risk men on AS

Perhaps unsurprisingly, your sitemaster was a little distracted on March 9 this year (by both the start of the COVID-19 chaos and by his birthday) and so he utterly missed what appears to be a rather important paper on the use of 5α-reductase inhibitors (5-ARIs) in men on active surveillance (AS) for management of low-risk forms of prostate cancer.

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Diabetes and risk for prostate cancer

There have long been suggestions that men already diagnosed with and receiving treatment for diabetes are at lower risk for a subsequent diagnosis of prostate cancer than non-diabetics. However, a very large, new, epidemiological analysis seems to suggest strongly that this may not be the case at all. … READ MORE …

Lifestyle, diet, exercise, and cancer

The Prostate Cancer Foundation (PCF) has recently issued a new “booklet” (it’s about 90 pages in length) entitled, The Science of Living Well, Beyond Cancer. … READ MORE …

Does eating mushrooms prevent prostate cancer?

Well, maybe, … at least among men living in in the Miyagi and Ohsaki prefectures, in Japan. … READ MORE …

Low-dose aspirin and prostate cancer-specific mortality

A newly published article — and an associated editorial — in the Annals of Internal Medicine has addressed the possible benefits of taking low-dose aspirin as a method to prevent the progression of newly diagnosed prostate cancer. … READ MORE …

No measurable benefit from supplements in the VITAL trial

Two sets of results from a major trial focused on the use of supplements to prevent cancer and heart disease are published today in the New England Journal of Medicine. … READ MORE …

Does lowering lipid levels really affect risk for prostate cancer and prostate cancer-specific mortality?

As our regular readers will be well aware, there have been a number of published papers suggesting associations between the use of statins and other lipid-lowering agents and risk for diagnosis with and progression of prostate cancer over time. … READ MORE …

Prostate cancer prevention and the VITAL study data

Two sets of data from the 5-year-long VITamin D and OmegA-3 TriaL (VITAL) were published this week in the New England Journal of Medicine. … READ MORE …

The “war” on cancer: are we “winning” or “losing” or what?

Clifton Leaf is a cancer survivor. He is also the Editor-in-Chief of Fortune magazine. And he has long argued that we may not be making the most astute decisions about how we are trying to find “the best” and “the rightest” ways to diagnose, treat, and manage cancer. … READ MORE …

Finasteride lowers risk for diagnosis with prostate cancer WITHOUT increased risk for prostate cancer-specific mortality

Something that most of us seem to have managed to “miss” at the American Urological Association (AUA) annual meeting in San Francisco in May was an update from Dr. Ian Thompson on the 25-year outcomes of the Prostate Cancer Prevention Trial (PCPT). It has the potential to be rather important! … READ MORE …

But can exercise lower risk for prostate cancer diagnosis or progression?

In an incidentally timely manner, the May issue of Annals of Oncology carries a systematic review and meta-analysis of data on physical activity and risk for prostate cancer. … READ MORE …

Exercise alone: no evidence that this can lower prostate cancer risk

It should come as no great surprise to anyone that one’s level of physical activity is not necessarily linked, on its own, to one’s risk for diagnosis with prostate cancer. … READ MORE …

Anticoagulation therapy and prostate cancer prevention

Today’s “hot news story” in the cancer world is that a very widely used drug called warfarin (often still known as Coumadin) may be able to protect people from  the risks of getting diagnosed with at least some cancers. But … READ MORE …

Of statins and the prevention and treatment of prostate cancer

The question of whether or not to take a statin to either prevent or actually help in the treatment of prostate cancer has potentially just become moot for many men in America … thanks to new guidance from the US Preventive Services Task Force (USPSTF). … READ MORE …

Statins in the prevention and management of prostate cancer: an update

A recent review article in the journal Nature Reviews: Urology has concluded that, while we are learning a lot more about the potential role(s) of statins in the prevention and management of prostate cancer, we still have no definitive evidence of their value. … READ MORE …