Can MRI data improve older, pre-treatment, prognostic methods?

An obvious but previously unanswered question has been whether adding data from the results of MRI scans to the data used in the Partin tables and in the pre-surgical Kattan nomogram (also known as the Memorial-Sloan Kettering Cancer Center or MSKCC nomogram) can improve the accuracy of these two commonly used prognostic methods. … READ MORE …

Projection of 15-year prostate cancer-specific survival after radical prostatectomy

For several years we have been able to use the Kattan nomograms to project 5-, 7-, and 10-year recurrence-free survival before and after radical prostatectomy for localized prostate cancer, based on the patient’s age, stage, Gleason score, and other relevant data (associated with biopsy or surgical findings, as appropriate). … READ MORE …

Improving on the Kattan nomogram through use of genetic data

There is an interesting new paper forthcoming in the Journal of Urology in which the research team describes how the addition of data from genetic profiling is able to improve the accuracy of the Kattan pre-treatment nomogram specifically in men believed to have localized prostate cancer at the time of diagnosis. … READ MORE …

The GEMCaP markers and the Kattan post-surgical nomogram

There is increasing concurrence that the addition of GEMCaP biomarker data may be able to improve the prognostic accuracy of the Kattan post-treatment nomogram. … READ MORE …

All the prostate cancer news for Friday, August 8

Today’s news items all focus on issues that are closely connected to the recent and controversial  guidelines issued by the US Preventive Services Task Force:

  • The accuracy of current methods for predicting the likelihood of clinically insignificant (indolent) prostate cancer
  • The management of patients found to have incidental prostate cancer on treatment for benign prostatic hyperplasia (BPH), and
  • The risks of overtreatment of men in their 70s and 80s after a diagnosis of prostate cancer … READ MORE …