Three major randomized clinical trials and a meta-analysis have proved that for most men waiting for early signs of recurrence after prostatectomy (e.g., three consecutive PSA rises or a PSA of 0.1 ng/ml) to give radiation gave the same outcome as immediate (“adjuvant”) radiation (see this link). But there are exceptions. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvaant, earky, mortality, outcome, post-prostatectomy, risk, salvage | 2 Comments »
A large randomized clinical trial, SAKK 09/10, found that a salvage radiation dose of 64 Gy over 32 treatments had equivalent biochemical outcomes compared to 70 Gy over 35 treatments. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: radiation, SAKK 09/10, salvage | Leave a comment »
It has always been troubling that only about half of all salvage radiation treatments after failure of radical prostatectomy are successful. Usually, only the prostate bed is treated. But sometimes recurrent patients (or those with persistently elevated PSA) receive salvage radiation to the pelvic lymph nodes as well, or subsequently. … READ MORE …
Filed under: Uncategorized | Tagged: dimensions, radiation, salvage | 15 Comments »
Although at least three randomized clinical trials have told us that adjuvant radiation after prostatectomy often affords better results than just taking a “wait-and-see” approach, … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, early, port-surgery, radiation, salvage | Leave a comment »
It is well known that prostate cancer is relatively radio-resistant compared to other kinds of cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, dose lewvel, radiation, risk, salvage | Leave a comment »
A research team at the University of California, Los Angeles (UCLA) is seeking participants for a randomized, Phase III, clinical trial of the utility of 68Ga-PSMA-11 PET/CT molecular imaging for planning of salvage radiotherapy after first-line treatment for localized prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: CT, free, gallium-68, PET, PSMA-11, radiation, salvage, scan, SRT, therapy | 4 Comments »
We didn’t expect to see data from the SPPORT trial for another 2 years, but the research team hit their recruitment goal early and have already been able to provide 5-year results. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, clinical, post-prostatectomy, radiation, recurrence, salvage, SPPORT | 14 Comments »
A randomized clinical trial of the 68Ga-PSMA-11 PET indicator for men with a recurrence after radical prostatectomy has just been initiated at the University of California Los Angeles (UCLA). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: gallium-68, PET, radiation, salvage, scan, trial | 1 Comment »
A recent presentation by Pouliot Frederick, MD, at the annual meeting of the Canadian Urological Association in Halifax, Nova Scotia, provided information on the roles of multiparametric MRI, [18F]choline, and 86Ga-PSMA PET/CT scans in determining the utility and value of salvage radiation therapy (SRT) for patients progressing after first-line surgery. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: radiation, risk, salvage, scan, Treatment | 3 Comments »
A large, well-done, confirmed, randomized clinical trial (RCT) is the only evidence that proves that one therapy is better than other. According to current consensus, this is deemed “Level 1a” evidence. But this high level of evidence is seldom available. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: decision-making, dose, outcome, radiation, risk, salvage | 2 Comments »
According to a media release issued on March 18 by EDAP TMS, the US healthcare insurance firm CIGNA has agreed to cover the use of high-intensity focal ultrasound (HIFU) as a second-line, salvage therapy for men with radiorecurrent prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: focused, HIFU, high-intensity, insurance, salvage, Treatment, ultrasound | Leave a comment »
The new PSMA-based PET scans provide a way to locate exactly where the cancer has spread to after an unsuccessful prostatectomy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: change, gallium-68, PET, plan, PSMA, radiation, salvage, scan, Treatment | 6 Comments »
A major new study adds to several other studies that show that, for men with adverse pathology, adjuvant radiation (ART) within 3 to 6 months of prostatectomy saves more lives compared to waiting until the PSA rises into the range of 0.1 to 0.5 ng/ml — salvage radiation (SRT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, radiation, salvage, therapy | 3 Comments »
The University of California, Los Angeles (UCLA) has announced a new clinical trial using stereotactic body radiation therapy (SBRT) for treatment of recurrent prostate cancer after failure of initial prostatectomy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: body, radiation, salvage, SBRT, stereotactic | 3 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 