Does being fit at 50 really NOT lower risk for prostate cancer?

A new study just published in JAMA Oncology appears to suggest that a man’s fitness at age 50 lowers his risk for cardiovascular disease, for colon cancer, and for lung cancer, but actually increases his risk for prostate cancer. One might justifiably wonder whether this makes sense. … READ MORE …

The Prostate Health Index (phi test) and the need for biopsy

It will come as no great surprise to regular readers that your Sitemaster has been less than enthusiastic to date about the potential of the Prostate Health Index or phi test as a tool for assessment of risk for prostate cancer. However, new data is starting to give him slightly greater hope regarding the value of this test. … READ MORE …

Use of CTCs to assess response to abiraterone acetate at 12 weeks on therapy

Back in 2011 we reported a presentation by Scher et al. indicating that circulating tumor cell counts (CTCs) could probably be used to monitor responses to abiraterone acetate (and perhaps other forms of drug therapy) in the treatment of men with metastatic, castration-resistant prostate cancer. … READ MORE …

After 10 years, risk of prostate cancer-specific mortality lower for high-risk patients

A paper presented at the annual meeting of the European Association of Urology (EAU) suggests that high-risk prostate cancer patients < 60 years of age at the time of radical prostatectomy are more likely to die from their cancer than from other causes during the first 10 years after their surgery. But after that, other causes of death become more likely. … READ MORE …

Enzalutamide shows positive outcome in TERRAIN trial

A media release issued today by Medivation and Astellas Pharma, based on data presented at the European Association of Urology meeting in Madrid, Spain, states that enzalutamide appears to extend progression-free survival (PFS) better than bicalutamide in the randomized, Phase II TERRAIN trial. … READ MORE …

Vitamin D as a treatment for low-risk prostate cancer? Not based on these data!

A presentation at a meeting of the American Chemical Society in Denver earlier this week suggested the possibility that men who took 4,000 IU of vitamin D every day for 60 days prior to a radical prostatectomy did better than similar men taking a placebo. … READ MORE …

“Angelina Jolie Pitt: Diary of a Surgery”

Whether one agrees with Ms. Angelina Jolie Pitt’s decisions about preventive surgery or not (and some will argue that her decisions are controversial), there is one thing that is very clear. She has used her celebrity to explain, very publicly, the decisions she has been making as a patient about her risk for cancer and what she is doing about that risk. … READ MORE …

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