The impact of bicycling on PSA levels … and risk for prostate cancer

Over the years it has been suggested, on and off, that bicycling may have impact on a man’s PSA levels and therefore on his potential risk for diagnosis of prostate cancer. However, there has never been any real evidence of such impact. … READ MORE …

Active surveillance, upgrading on repeat biopsy, and consequent management

In February this year we commented on an article that argued in favor of active surveillance as an appropriate initial management strategy for “favorable” intermediate-risk prostate cancer. … READ MORE …

Tokai initiates trial of galeterone in men with AR-V7-positive mCRPC

According to information released earlier today by Tokai Pharmaceuticals, the company has started to enroll patients with AR-V7-positive, metastatic, castration-resistant prostate cancer (mCRPC) into a randomized Phase III clinical trial of treatment with galeterone. … READ MORE …

Should all patients starting on ADT be on a statin too?

A newly published article in JAMA Oncology has now suggested that adding a statin to a patient’s treatment regimen at initiation of androgen deprivation therapy (ADT) may significantly impact time to disease progression among men diagnosed with progressive, hormone-sensitive prostate cancer. … READ MORE …

Does diagnosis/treatment for prostate cancer increase risk for colorectal cancer too?

A newly published study in the journal of Cancer Control has again suggested the possibility that men treated for prostate cancer may be at elevated risk for a secondary diagnosis of colorectal cancer by comparison with similar men never diagnosed with prostate cancer. … READ MORE …

Assessing the “value” of new drugs in the treatment of [prostate] cancer

Yesterday the American Society of Clinical Oncology (ASCO) issued the initial draft of “a conceptual framework for assessing the value of new cancer therapies based on treatment benefits, toxicities, and costs.” ASCO is interested in getting feedback from its members and from the patient community too. … READ MORE …

Another new way to diagnose prostate cancer more accurately?

A news item on Friday in the Rochester Democrat and Chronicle describes research ongoing at the Rochetster Institute of Technology into another new way to identify men at high risk for prostate cancer — but using targeted dying agents that will “stick” to the membranes of prostate cancer cells. … READ MORE …

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